With the first draft of the human genome project in the public domain and full analyses of model genomes now available, the subject matter of 'Principles of Genome Analysis and Genomics' is even 'hotter' now than when the first two editions were published in 1995 and 1998. In the new edition of this very practical guide to the different techniques and theory behind genomes and genome analysis, Sandy Primrose and new author Richard Twyman provide a fresh look at this topic. In the light of recent exciting advancements in the field, the authors have completely revised and rewritten many parts of the new edition with the addition of five new chapters. Aimed at upper level students, it is essential that in this extremely fast moving topic area the text is up to date and relevant
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Preface, vii
Abbreviations, ix

1 Setting the scene: the new science of genomics
2 The organization and structure of genomes
3 Subdividing the genome
4 Assembling a physical map of the genome
5 Sequencing methods and strategies
6 Genome annotation and bioinformatics
7 Comparative genomics
8 Protein structural genomics
9 Global expression profiling
10 Comprehensive mutant libraries
11 Mapping protein interactions
12 Applications of genome analysis and genomics

References
Index